Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep848 | Pituitary and Neuroendocrinology | ECE2023

Opposite tumoral and hormonal responses to low-dose pasireotide in Cushing’s Disease

Serban Andreea , Zampetti Benedetta , Saladino Andrea , Chiodini Iacopo , Cozzi Renato

Pasireotide (Pas) is a multireceptor-targeted somatostatin analogue approved for the treatment of patients with Cushing’s Disease (CD) who fail or are poor candidates to surgery. Pas markedly improves signs and symptoms of the disease, reduces urinary free cortisol (UFC) up to its normalization in 55% of patients and pituitary tumour size in up to 100%. Here we present a patient with severe recurrent CD treated with Pas and showing opposite results between hormonal levels...